A good antigen quality is key point to generate efficient antibodies. We accompany you in the design and the production of the most convenient antigen that will stimulate the host’s immune response and favor antibody production.
We offer a full antigen service
Various antigens can be used, such as: peptides, proteins, bacteria, inactivated viruses, transfected cells, small molecules…
Biosafety level 3 (BL3) antigens can be handled in our facilities.
Customized bioinformatics studies taking into account critical features
Preliminary work for optimization of antigen design,
Homology with non-relevant proteins,
B epitopes prediction,
Protein structure analysis, …
- Peptides with post-translational modifications, cyclization, …
- Conjugation to carrier proteins
- Full-length proteins, protein fragments, poly-epitopes, fusion proteins, …
We routinely produce peptides for immunization purposes, and our peptide design service is based on specific algorithms for the most efficient immunogen generation.
Peptides bearing various post-translational modifications can be produced, including phosphorylation, methylation, acetylation, and many others. Within our subsidiary AnaSpec Inc, we are experienced to generate the most complex peptides.
Protein production, purification and validation
- Expression and co-expression
- Bacterial and eukaryotic host cells
- Renaturation and purification of fastidious targets
- Optimization of production yields on request